Cycobalamin ke e 'ngoe ea li-complexes tsa vithamine B, e nang le phello e matla ea anti-pernicious anemia. Ke lebitso le fanoeng ke kristale ea vithamine B12, ntho ea bohlokoa bakeng sa nts'etsopele ea libaktheria le liphoofolo. Ntle le C, H, O, N, P le Co, aD-ribose conjugate ea 5,6-dimethe-rbenzimidazole ke karolo ea sebopeho sa eona. AR Todd et al. beha pele mokhoa oa sebopeho, o bitsoang cyanocobalamin hobane cyano e hokahanngoa holim'a cobalt. Ho monya ho hoholo ka tharollo ea metsi ke 278,361,548 nm. Ka 1948, E. L.Rickes oa United States le E. Ho tloha ka nako eo, ntho ena e boetse e fumanoe ho tsoa ho actinomycete e itseng (StrePtomyces griseum). Cyanocobalamin hape ke karolo ea kholo ea likolobe le litsuonyana, 'me ke ntho e tšoanang le ea protheine ea liphoofolo e hlokahalang bakeng sa ho qhotsoa ha lehe. Vithamine B12, e fuoang bakuli ba nang le mafu a kotsi ho 150 micrograms, e ka eketsa lisele tse khubelu tsa mali ka makhetlo a ka bang 2, 'me 3-6 micrograms e ka boela ea hlahisa liphello. Ka vivo, e tsamaisoa ka mali ka mokhoa oa ho kopanngoa le protheine ea trans-cobalamin (a-globular protein), 'me e teng ka mokhoa oa coenzyme liseleng tse fapaneng. Hammoho le folic acid, e ameha metabolism ea methyl phetiso le tlhahiso e sebetsang ea methyl. 'Me e be ntho ea bohlokoa ea purine, pyrimidine le biosynthesis e meng.
